[Dosimetric perturbation due to scattered rays released by a gold marker used for tumor tracking in external radiotherapy].
نویسندگان
چکیده
Image-guided radiation therapy using a gold marker-based tumor tracking technique provides precise patient setup and monitoring. However, the marker consists of high-Z material, and the resulting scattered rays tend to have adverse effects on the dose distribution of radiotherapy. The purpose of this study was to evaluate the dosimetric perturbation due to the use of a gold marker for radiotherapy in the lungs. The relative dose distributions were compared with film measurement, Monte Carlo simulation, and XiO calculation with the multi grid superposition algorithm using two types of virtual lung phantoms, which were composed of tough water phantoms, tough lung phantoms, cork boards, and a 2.0-mm-diameter gold ball. No dose increase and decrease in the vicinity of the gold ball was seen in the XiO calculations, although it was seen in the film measurements and the Monte Carlo simulation. The dose perturbation due to a gold marker cannot be evaluated using XiO calculation with the superposition algorithm when the tumor is near a gold marker (especially within 0.5 cm). To rule out the presence of such dose perturbations due to a gold marker, the distance between the gold marker and the tumor must therefore be greater than 0.5 cm.
منابع مشابه
A Monte Carlo Study on Dose Enhancement by Homogeneous and Inhomogeneous Distributions of Gold Nanoparticles in Radiotherapy with Low Energy X-rays
Background: To enhance the dose to tumor, the use of high atomic number elements has been proposed.Objective: The aim of this study is to investigate the effect of gold nanoparticle distribution on dose enhancement in tumor when the tumor is irradiated by typical monoenergetic X-ray beams by considering homogeneous and inhomogeneous distributions of gold nanoparticles (GNPs) in the tumor.Method...
متن کاملA quantitative investigation on lung tumor site on its motion tracking in radiotherapy with external surrogates
Introduction: In external beam radiotherapy each effort is done to deliver 3D dose distribution onto the tumor volume uniformly, while minimizing the dose to healthy organs at the same time. Radiation treatment of tumors located at thorax region such as lung and liver has a challenging issue during target localization since these tumors move mainly due to respiration. There are...
متن کاملA study on the accuracy of motion tracking of thoracic tumors at radiotherapy with external surrogates
Introduction: In radiotherapy with external surrogates, exact information of tumor position is one of the key factors that improves treatment delivery. Many dynamic tumors in thorax region of patient move mainly due to respiration and are known as intra-fractional motion error that must be compensated, as well. One of clinical strategy is using Stereotactic Body Radiation Thera...
متن کاملInvestigation of the dose enhancement effect due to gold nanoparticles at 18 MV radiotherapy using MAGIC-f and Monte Carlo methods Thoraco-Lumbar spinal cord fMRI in 3T Magnetic field
Introduction: Normoxic MAGIC-f polymer gels are established dosimeters used for three dimensional dos uantifications in radiotherapy. The high atomic number nanoparticles such as gold are nov adiosensitizers used to enhance doses delivered to tumors. The aim of this study was t vestigate the effect of gold nanoparticles (GNPs) in enhancing percentage depth doses (PDD ithin the...
متن کاملMegavoltage dose enhancement of gold nanoparticles for different geometric set-ups: Measurements and Monte Carlo simulation
Background: Gold nanoparticles (GNPs) have been shown as a good radiosensitizer. In combination with radiotherapy, several studies with orthovoltage X-rays have shown considerable dose enhancement effects. This paper reports the dose enhancement factor (DEF) due to GNPs in 18 megavoltage (MV) beams. Materials and Methods: Different geometrical 50-nm GNPs configurations at a concentrati...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Nihon Hoshasen Gijutsu Gakkai zasshi
دوره 67 9 شماره
صفحات -
تاریخ انتشار 2011